Comprehensive Nursing Pharmacology Q 274

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The nurse is caring for a client who is receiving fluorouracil (Adrucil). Which of the following symptoms would necessitate the nurse to immediate discontinuation of the medication?

  

     A. Palmar-plantar erythrodysesthesia

     B. Ataxia

     C. Constipation

     D. Insomnia

    

    

Correct Answer: B. Ataxia.

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During the administration of Fluorouracil. Monitor for symptoms of dizziness, weakness, and ataxia which are signs of cerebral dysfunction that would immediately lead to the discontinuation of the medication.

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Option A: This is characterized by skin rash, swelling, redness, pain, and/or peeling of the skin on the palms of hands and soles of feet. Is usually a mild symptom that would only require a reduction of the dosage.

Option C: Diarrhea is a related sign, not constipation.

Option D: Insomnia is not a related symptom of this medication.

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