Cardiovascular Drugs and Medications Q 50

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Which of the following vitamins may not be absorbed properly when giving bile acid sequestrants?

  

     A. Vitamin B

     B. Vitamin C

     C. Vitamin B12

     D. Vitamin K

    

    

Correct Answer: D. Vitamin K

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Vitamin K absorption may be reduced when giving these drugs. The only fat-soluble vitamin here is vitamin K, which is synthesized in the liver. Bile acid sequestrants may prevent absorption of folic acid and the fat-soluble vitamins A, D, E, and K. Other medications and vitamin supplements should be taken one hour before or four to six hours after bile acid sequestrants for optimal absorption.

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Option A: B vitamins play a vital role in maintaining good health and well-being. As the building blocks of a healthy body, B vitamins have a direct impact on your energy levels, brain function, and cell metabolism. Vitamin B complex helps prevent infections and helps support or promote cell health.

Option B: Vitamin C is a water-soluble vitamin, antioxidant, and essential cofactor for collagen biosynthesis, carnitine and catecholamine metabolism, and dietary iron absorption. Humans are unable to synthesize vitamin C, so they can only obtain it through dietary intake of fruits and vegetables. Citrus fruits, berries, tomatoes, potatoes, and green leafy vegetables are excellent sources of vitamin C.

Option C: Vitamin B12 (Cobalamin) is a water-soluble vitamin that is derived from animal products such as red meat, dairy, and eggs. Intrinsic factor is a glycoprotein that is produced by parietal cells in the stomach and necessary for the absorption of B12 in the terminal ileum. Once absorbed, B12 is used as a cofactor for enzymes that are involved in the synthesis of DNA, fatty acids, and myelin.

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