NCLEX-PN Practice Q 54

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A postoperative client has an order for Demerol (meperidine) 75mg and promethazine (Phenergan) 25mg IM every 3–4 hours as needed for pain. The combination of the two medications produces a/an:

  

     A. Antagonist effect

     B. Excitatory effect

     C. Synergistic effect

     D. Agonist effect

    

    

Correct Answer: C. Synergistic effect

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Option C: The combination of the two medications produces an effect greater than that of either drug used alone.

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Option A: Antagonist effects are those in which the actions of the drugs oppose one another.

Option B: The drugs would have a combined depressing, not excitatory, effect.

Option D: Agonist effects are similar to those produced by chemicals normally present in the body.

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