Comprehensive Nursing Pharmacology Q 244

---

A client is receiving methotrexate (Rheumatrex) for a series of chemotherapy. Which of the following medication should be readily available to avoid toxicity?

  

     A. mesna (Mesnex)

     B. vigabatrin (Sabril)

     C. leucovorin (Folinic acid)

     D. oseltamivir (Tamiflu)

    

    

Correct Answer: C. leucovorin (Folinic acid)

---

Large doses of Methotrexate (Rheumatrex) may lead to harmful effects in the body. Leucovorin is administered to prevent its toxicity.

---

Option A: Mesna is given with ifosfamide to decrease the potential of ifosfamide induced cystitis.

Option B: Vigabatrin is an anticonvulsant.

Option D: Oseltamivir is an influenza antiviral medication.

---