Comprehensive Nursing Pharmacology Q 245



A pregnant client is receiving magnesium sulfate therapy for the control of preeclampsia. A nurse discovers that the client is encountering toxicity from the medication in which of the following assessments?
  
     A. Respirations of 10 breaths per minute.
     B. Presence of deep tendon reflex.
     C. Urine output of 25 ml/hr.
     D. Serum magnesium level of 7 mEq/L.
    
    

Correct Answer: A. Respirations of 10 breaths per minute.

Magnesium sulfate is a central nervous system depressant and anticonvulsant. It can cause smooth muscle relaxation. Signs of magnesium sulfate toxicity relate to the central nervous system depressant effects of the medication and include respiratory depression, decreased urine output, loss of deep tendon reflexes, hypotension and a decreased maternal and fetal heart rate.

Option B: Deep tendon reflexes must be present.
Option C: Urine output should be maintained at 25-30ml/hr.
Option D: Normal range for magnesium is between 4-7 mEq/L